langendorff perfusion set-up (Hugo Sachs Elektronik)
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Langendorff Perfusion Set Up, supplied by Hugo Sachs Elektronik, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/langendorff+perfusion+set-up/langendorff+perfusion+set+up/10__1113_slash_ep088165-48-12-15
Average 90 stars, based on 1 article reviews
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other:Article Title: Arrhythmogenic drugs can amplify spatial heterogeneities in the electrical restitution in perfused guinea-pig heart: An evidence from assessments of monophasic action potential durations and JT intervals Article Snippet: The chest was opened, the hearts were immediately excised, mounted on a Article Title: Determinants of slowed conduction in premature ventricular beats induced during programmed stimulations in perfused guinea-pig heart Article Snippet: All rights reserved. chest was opened, the hearts were immediately excised, mounted on a Article Title: Effects of Na + channel blockers on the restitution of refractory period, conduction time, and excitation wavelength in perfused guinea-pig heart Article Snippet: The chest was opened, the hearts were immediately excised, mounted on a Article Title: Effects of antiarrhythmics on the electrical restitution in perfused guinea‐pig heart are critically determined by the applied cardiac pacing protocol Article Snippet: The chest was opened and the hearts were immediately excised, mounted on a Article Title: Antiarrhythmic drug effects on premature beats are partly determined by prior cardiac activation frequency in perfused guinea‐pig heart Article Snippet: The chest was opened, the hearts were immediately excised, mounted on a Article Title: Effects of antiarrhythmics and hypokalemia on the rate adaptation of cardiac repolarization. Article Snippet: Objectives.. In normal conditions, sudden heart rate acceleration provokes a rapid reduction in ventricular action potential duration (APD).. The protracted APD rate adaptation favors early afterdepolarizations and precipitates arrhythmia. Article Title: Assessments of the QT/QRS restitution in perfused guinea-pig heart can discriminate safe and arrhythmogenic drugs. Article Snippet: Introduction: Drug-induced arrhythmia remains a matter of serious clinical concern, partly due to low prognostic value of currently available arrhythmic biomarkers.. Methods: This study examined whether arrhythmogenic risks can be predicted through assessments of the rate adaptation of QT interval, ventricular effective refractory period (ERP), or the QT/QRS ratio, in perfused guineapig hearts.. Results: When the maximum restitution slope was taken as a metric of proarrhythmia, neither QT interval nor ERP measurements at progressively increased pacing rates were found to fully discriminate arrhythmogenic drugs (dofetilide, quinidine, flecainide, and procainamide) from those recognized as safe antiarrhythmics (lidocaine and mexiletine). Article Title: Determinants of slowed conduction in premature ventricular beats induced during programmed stimulations in perfused guinea-pig heart. Article Snippet: The chest was opened, and the hearts were immediately excised, mounted on a Langendorff perfusion set-up ( |
